We routinely achieve >95% purity (HPLC) for standard peptides (<30 amino acids). For complex modifications (e.g., phosphorylations, fluorescent labels), purity typically exceeds 85-90%, with detailed analytical reports (HPLC/MS) provided for verification.
Yes. We optimize synthesis protocols for challenging sequences (e.g., high ฮฒ-sheet propensity, poly-Arg/Lys, or Cys-rich peptides) using specialized resins and cleavage conditions. Typical purity remains >80%, with MS/MS validation.
We support N-terminal (acetylation, FITC, biotin), C-terminal (amidation, carboxylation), side-chain (phosphorylation, glycosylation), and non-natural amino acids (e.g., D-amino acids). Custom modifications are available upon consultation.
Every peptide undergoes mass spectrometry (MALDI-TOF or ESI-MS) for MW confirmation and, if requested, MS/MS sequencing. For critical applications (e.g., immunology), we provide HPLC chromatograms and CoA.
Standard delivery: 2-3 weeks (โฅ85% purity). Rush service: 7-10 business days (purity-adjusted). Complex modifications or long peptides (>50 aa) may require additional time.
Peptides are delivered as lyophilized powder in sterile vials. Buffered solutions (e.g., PBS, acetic acid) can be prepared upon request (additional QC for solubility testing).
We employ controlled oxidation (air/mild oxidants) or orthogonal protection (e.g., Fmoc-Cys(Trt)/Cys(Acm)) for 1-3 disulfide bonds. Cyclization efficiency is verified by HPLC/MS.
Scales range from 1 mg (research-grade) to 100 mg (preclinical/assay development). Bulk quantities (>500 mg) are synthesized under GMP-like conditions upon request.
Yes. We offer parallel synthesis for systematic libraries (e.g., overlapping peptides, scanning mutations) with 85-95% purity per variant. Plates/microarrays are available.
For cell culture applications, we provide endotoxin testing (<0.1 EU/ฮผg via LAL assay) and sterile filtration upon request.
Lyophilized peptides are stable at -20ยฐC (desiccated). For long-term storage (>1 year), -80ยฐC is recommended. Avoid repeated freeze-thaw cycles for solutions.
We provide solubility guidance based on sequence (e.g., adding charged residues, DMSO/acid solubilization) and can reformulate problematic peptides (e.g., PEGylation) at no extra cost.
